Ph.D.: Wisconsin (2010)
Year Appointed: 2013
Rank: Assistant Professor
Areas of Interest
My position is focused on maize translational genomics. One area of interest is exploring maize genotypic diversity and identifying genetic elements underlying important agronomic traits such as yield component traits. Another area of interest is in characterizing the maize pan genome, elucidating the origin of dispensable genes, and understanding the effect of core and dispensable genes and transcripts on phenotypic variation. I am also interested in the molecular mechanisms underlying heterosis in maize and using this knowledge to establish heterotic groups in non-model grass species. In addition to my research responsibilities, I teach a graduate level plant genomics course Agro 5431: Applied Plant Genomics and Bioinformatics.
Haase, N., T. Beissinger, Hirsch, B. Vaillancourt, S. Deshpande, K. Barry, C.R. Buell, S. Kaeppler, N. de Leon. 2015. Shared Genomic Regions Between Derivatives of Large Segregating Population of Maize Identified Using Bulked Segregant Analysis Sequencing and Traditional Linkage Analysis. Genes Genomes and Genetics. 5:1593-1602.
Hirsch, C.D., N. Springer, N. Hirsch. 2015. Genomic Limitations to RNAseq Expression Profiling. The Plant Journal. 84(3):491-503.
Makarevitch, I., A. Waters, P. West, M. Stitzer, C. Hirsch, J. Ross-Ibarra, N. Springer. 2015. Transposable elements contribute to activation of maize genes in response to abiotic stress. PLoS Genetics. 11(1):e1004915.
Stelpflug, S., R. Sekhon, B. Vaillancourt, C. Hirsch, C.R. Buell, N. de Leon, S. Kaeppler. 2015. An expanded maize gene expression atlas based on RNA-sequencing and its use to explore root development. The Plant Genome. doi:10.3835/plantgenome2015.04.0025.
Beissinger, T., C. Hirsch, B. Vaillancourt, S. Deshpande, K. Barry, C.R. Buell, S. Kaeppler, D. Gianola, N. de Leon. 2014. A Genome-Wide Scan for Evidence of Selection in a Maize Population Under Long-Term Artificial Selection for Ear Number. Genetics. 196(3):829-840
Burton, A., J. Johnson, J. Foerster, C. Hirsch, C.R. Buell, M. Hanlon, S. Kaeppler, K. Brown, J. Lynch. 2014. QTL mapping and phenotypic variation for root architectural traits in maize (Zea mays L.). Theoretical and Applied Genetics. 127:2293-2311.
Childs, K., A. Nandety, C. Hirsch, E. Gongora-Castillo, J. Schmutz, S. Kaeppler, M. Casler, C.R. Buell. 2014. Generation of Transcript Assemblies and Identification of Single Nucleotide Polymorphisms from Seven Lowland and Upland Cultivars of Switchgrass. The Plant Genome. 7:–.
Douches, D., C. Hirsch, N.Manrique-Carpintero, A. Massa, J. Coombs, M. Hardigan, D. Bisognin, W. De Jong, C.R. Buell. 2014. The Contributions of the Solanaceae Coordinated Agricultural Project to Potato Breeding. Potato Research. 57:215-224.
Hirsch, C. 2014. Genomic Sequence and Structural Diversity in Plants. In: Bell E., Bond J., Klinman J., Masters B., Wells R. (Ed.) Molecular Life Sciences: An Encyclopedic Reference: SpringerReference (www.springerreference.com). Springer-Verlag Berlin Heidelberg.
Hirsch, C.D., J. Evans, C.R. Buell, C.N. Hirsch. 2014. Reduced representation approaches to interrogate genome diversity in large, repetitive plant genomes. Briefings in Functional Genomics. 13(4): 257-267.
Hirsch, C.D, J. Hamilton, K. Childs, J. Cepela, E. Crisovan, B. Vaillancourt, C.N. Hirsch, M. Habermann, B. Neal, C.R. Buell. 2014. Spud DB: A resource for mining sequences, genotypes, and phenotypes to accelerate potato breeding. The Plant Genome. 7:–.
Hirsch, C., J. Foerster, J. Johnson, R. Sekhon, G. Muttoni, B. Vaillancourt, N. de Leon, S. Kaeppler, C.R. Buell. 2014. Insights into the Maize Pan-Genome and Pan-Transcriptome. Plant Cell. 26:121-135.
Hirsch, C., S. Flint-Garcia, T. Beissinger, S. Eichten, S. Deshpande, K. Barry, M. McMullen, J. Holland, E. Buckler, N. Springer, C.R. Buell, N. de Leon, S. Kaeppler. 2014. Insights into the effects of long-term artificial selection on seed size in maize. Genetics. 198(1):409-421.
Salvo, S., C. Hirsch, C.R. Buell, S. Kaeppler, H. Kaeppler. 2014. Phenotypic and transcriptional analysis of divergently selected maize populations reveals the role of developmental timing in seed size determination. Whole transcriptome profiling of maize during early somatic embryogenesis reveals altered expression of stress factors and embryogenesis-related genes. PLoSOne. 9(10):e111407.
Sekhon, R., C. Hirsch, K. Childs, M. Breitzman, P. Kell, S. Duvick, E. Spalding, C.R. Buell, N. de Leon, S. Kaeppler. 2014. Phenotypic and transcriptional analysis of divergently selected maize populations reveals the role of developmental timing in seed size determination. Plant Physiology. 165:658-669.
Beissinger, T., C. Hirsch, R. Sekhon, J. Foerster, J. Johnson, G. Muttoni, B. Vaillancourt, C.R. Buell, S. Kaeppler, N. de Leon. 2013. Marker density and read-depth for genotyping populations using genotyping-by-sequencing. Genetics. 193:1073-1081.
Hirsch, C.N., C.D. Hirsch, K. Felcher, J. Coombs, D. Zarka, A. Van Deynze, W. De Jong, R. Veilleux, S. Jansky, P. Bethke, D. Douches, C.R. Buell. 2013. Retrospective view of North American potato (Solanum tuberosum L.) breeding in the 20th and 21st centuries. Genes Genomes and Genetics. 3:1003-1013.
Hirsch, C., C.R. Buell. 2013. Tapping the promise of genomics in species with complex, non-model genomes. Annual Review of Plant Biology. 64:89-110.
Jansen, C., N. de Leon, N. Lauter, C. Hirsch, L. Ruff, T. Lübberstedt. 2013. Genetic and morphometric analysis of cob architecture and biomass-related traits in the intermated B73xMo17 recombinant inbred lines of maize. BioEnergy Research. 6:903-916.
Sekhon, R., R. Briskine, C. Hirsch, C. Myers, N. Springer, C.R. Buell, N. de Leon, S. Kaeppler. 2013. Maize gene atlas developed by RNA sequencing and comparative evaluation of transcriptomes based on RNA sequencing and microarray. PLoSOne. 8(4):e61005.
Felcher, K., J. Coombs, A. Massa, C. Hansey, J. Hamilton, R. Veilleux, C.R. Buell, D. Douches. 2012. Integration of Two Diploid Potato Linkage Maps with the Potato Genome Sequence. PLoSOne. 7(4):e36347.
Hansey, C., B. Vaillancourt, R. Sekhon, N. de Leon, S. Kaeppler, C.R. Buell. 2012. Maize (Zea mays L.) Genome Diversity as Revealed by RNA-sequencing. PLoSOne. 7(3):e33071.
Smith, A., C. Hansey, S. Kaeppler. 2012. TCUP: A novel hAT transposon active in maize tissue culture. Frontiers in Plant Science. 3:6.
Davidson, R.**, C. Hansey**, M. Gowda, K. Childs, H. Lin, B. Vaillancourt, R. Sekhon, N. de Leon, S. Kaeppler, N. Jiang, C.R. Buell. 2011. Utility of RNA-seq for Analysis of Maize Reproductive Transcriptomes. The Plant Genome. 4:191-203. **These authors contributed equally to this work.
Hamilton, J., C.Hansey, B. Whitty, K. Stoffel, A. Massa, A. Van Deynze, W. De Jong, D. Douches, C.R. Buell. 2011. Single Nucleotide Polymorphism Discovery in Elite North American Potato Germplasm. BMC Genomics. 12:302.
Hansey, C., J. Johnson, R. Sekhon, S. Kaeppler, N. de Leon. 2011. Genetic Diversity of a Maize Association Population with Restricted Phenology. Crop Sci. 51:704-715.
Hansey, C. and N. de Leon. 2011. Biomass Yield and Cell Wall Composition of Corn with Alternative Morphologies Planted at Variable Densities. Crop Sci. 51:1005-1015.
Sekhon, R., H. Lin, K. Childs, C. Hansey, C.R. Buell, N. de Leon, S. Kaeppler. 2011. Genome-wide atlas of transcription through maize development. Plant Journal. 66(4):553-563.
de Leon, N. and C. Hansey. 2010. Breeding Corn for Lignocellulosic Biofeedstock Production. Proc. Annu. Corn Sorghum Res. Conf., 65th, Chicago, IL. 7-10 Dec. 2010. American Seed Trade Association, Inc, Washington, DC.
Hansey, C., A. Lorenz and N. de Leon. 2010. Cell Wall Composition and Ruminant Digestibility of Various Maize Tissues Across Development. BioEnergy Research. 3(1): 28-37.
Lorenz, A.J., N. de Leon, C. Hansey, J. Coors and S. Kaeppler. 2010. Genetic Analysis of Agronomic and Cell Wall Traits Relevant to Cellulosic Ethanol Production in Maize (Zea mays L.). Crop Sci. 50: 1-11.